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Extending Cardiovascular
Detection Infrastructure

A regulated Software as a Medical Device platform designed for upstream patient encounters

Health systems interact with large patient populations outside cardiology. Embedding upstream detection into routine workflows surfaces latent signals, structures clinical data, and supports more effective patient routing.

This improves referral precision, strengthens patient mix, and captures clinical and program value that would otherwise remain outside the system.

The Upstream Detection Gap

The next phase of cardiovascular program growth will be driven by upstream detection, patient identification and routing efficiency.

Healthcare systems generate strong diagnostic signals, but they are concentrated too far downstream and rarely available where initial routing decisions are made.

This is where patient mix is shaped, and where small improvements in flow and structured data capture can scale into meaningful clinical and economic impact.

Without upstream detection infrastructure, referral pathways are driven by limited and inconsistent input, leading to inefficiency, capacity strain, suboptimal patient mix, program losses, and delayed care.

  • 10.6M

    Americans with clinically significant VHD

    ACC/AHA 2021

  • ~ 1 M

    New patients reach clinical significance annually

    Consistent incidence

  • 50%

    AS patients undiagnosed past age 65

    PREVUE Valve 2025

  • < 30%

    Upstream encounters producing a cardiac signal

    Detection gap

  • 2-5 years

    Typical delay from onset to program visibility

    PARTNER Trial

A Regulated Cardiac Signal Analysis Platform

Delivered through smartphones already embedded in clinical environments.

Stethophone Pro is a regulated Software as a Medical Device platform designed to extend cardiovascular detection infrastructure into upstream patient encounters.

Operating through clinical smartphone programs, cardiac findings are captured early in the care pathway - becoming structured, actionable signals that support patient routing for cardiology and structural heart programs.

Population in health system

Millions of patients

Detection Opportunity

Upstream clinical encounters

  • Primary care
  • Urgent care
  • Pre-op
  • Hospital intake

Bioacoustic signal detection

Stethophone AI-phonoscopy

Structured triage signal

Objective cardiac signal evidence

Optimized
  • Echocardiography referral

    Diagnostic imaging
  • Valve disease diagnosis

    Structural heart evaluation
  • TAVR / SAVR program

    Intervention and follow-up

Deep Heart Sound Characterization

Transforming cardiac sounds into structured clinical signals

Stethophone Pro performs deep heart sound characterization, analyzing cardiac acoustic patterns and translating them into interpretable clinical outputs.

Using AI Phonoscopy, the platforms evaluates cardiac sound and generates findings that support clinical interpretation, patient routing, and downstream decision making.

This approach enables cardiovascular programs to recognize patterns earlier in the care pathway - patterns that might otherwise remain transient within routine examinations.

Cardiac Sound

Captured during routine clinical evaluation.

At this stage, cardiac cycles are obscured by ambient noise, respiratory sounds, and mechanical interference.

Acoustic Filtering

Proprietary algorithms process cardiac sounds into clinically relevant, interpretable signals.

Temporal Alignment

Aligns heart sounds with the cardiac cycle to define the timing of S1 and S2.

Clinical Interpretation

Identifies clinically relevant heart sound patterns, using murmurs as indicators of structural abnormalities.

Deep Heart Sound Characterization

Transforms cardiac sounds into clinically interpretable findings through advanced signal processing.

Clinical Output

Structured cardiac signal with labeled features for clinical use.

Clinician in medical scrubs with a smartphone running Stethophone in the chest pocket Clinician in medical scrubs with a smartphone running Stethophone in the chest pocket

Enterprise Deployment

Designed to integrate seamlessly into existing clinical mobile device programs and institutional workflows.

By operating through smartphones already deployed across health systems, Stethophone Pro extends detection infrastructure without adding operational burden.

This enables scalable upstream detection, consistent data structuring, and reliable signal generation across distributed care settings. Which is critical for improving patient routing and maintaining real-world adoption.

Avoiding typical equipment burdens:

  • Charging and Power
  • Device Tracking
  • New Cleaning Protocols
  • Equipment Ownership
Monitor displaying Stethophone Heart Examination Summary interface Clinician holding a smartphone with Stethophone examination interface

AI Phonoscopy

A cardiac signal analysis framework designed for scalable detection infrastructure.

AI Phonoscopy is Sparrow's foundational framework for interpreting cardiac sound through structured acoustic analysis.

The system transforms bioacoustic input into standardized, clinically meaningful signals to enable upstream detection, consistent data structuring, and integration into patient routing pathways across a wide range of cardiovascular indications.

Initial indications are delivered through regulated modules, while the platform architecture supports continuous expansion of detection capabilities over time.

Increasing Flow and Precision within a Strategic Service Lines

    • Urgent Care
    • Pre-Admission/Anesthesia Testing
    • Hospital Admission/Intake
    • Internal Medicine
    • Primary Care

    Distributed care settings to the list

    Stethophone Pro upstream cardiac signal detection (AI phonoscopy / bioacoustic analysis)
    Stethophone Pro structured triage / routing signal
    • Cardiovascular Care Routing
    • Structural Heart Program Yield
    • Initial Diagnostics Cascade
    • Valve Program Continuity
  1. Program Outcomes:

    • Earlier intervention
    • Lower mortality
    • Fewer emergency admissions
    • Improved care coordination
  2. Cardiovascular Program Gravity:

    • Program reputation
    • Referral capture
    • Regional patient inflow
    • Structural Heart Program Yield

Detection Across the Care Network

Extending cardiac detection infrastructure beyond specialist environments.

Leading programs increasingly recognize upstream detection as a core lever for growth, enabling earlier identification of appropriate patients and more effective patient routing into established care pathways.

Earlier signal generation expands imaging activity, strengthens longitudinal surveillance, improves referral precision, and enhances patient mix - ultimately supporting procedural volumes and program sustainability.

The economic and patient impact extends beyond structural heart interventions, influencing the broader cardiology service line across the network.

Developed with Leading Cardiovascular Clinicians and Researchers

Stethophone Pro has been developed in collaboration with clinicians and researchers involved in advancing modern heart practice.
Clinical research and real-world deployment programs continue to evaluate how structured cardiac sound analysis can support upstream detection, earlier recognition of cardiovascular disease, and more effective patient routing within routine care pathways.
Dr. Jamie McCabe

Dr. Jamie McCabe

Section Head, Structural Heart Therapies & Director of the Center for Innovation in Invasive Cardiology at Beth Israel Deaconess Medical Center

Dr. William Nicholson

Director of Interventional Cardiology - Emory University Professor of Medicine

Dr. Duane Pinto

CMO JenaValve

Dr. Philippe Généreux

Director Structural Heart - Morristown Medical Center.

Dr. Jamie McCabe

Section Head, Structural Heart Therapies & Director of the Center for Innovation in Invasive Cardiology at Beth Israel Deaconess Medical Center

Dr. William Nicholson

Director of Interventional Cardiology - Emory University Professor of Medicine

Dr. Duane Pinto

CMO JenaValve

Dr. Philippe Généreux

Director Structural Heart - Morristown Medical Center.

Institutional Deployment

Programs exploring deployment models or clinical pathway integration can request additional materials.

Health systems can integrate Stethophone Pro into existing clinical workflows and mobile device programs with minimal operational change.

Deployment supports upstream detection within routine patient encounters, generating structured cardiac signals that feed into patient routing and escalation pathways.

Request a deployment brief outlining workflow placement, governance considerations, and how structured cardiac signal analysis integrates into referral and care pathways.

Smartphone being used for cardiac examination on medical mannequin
Smartphone displaying cardiac spectrogram analysis